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The accumulation of damaged DNA in the cytoplasm, which serves as a damage-associated molecular pattern (DAMP) to be recognized by DNA sensors, including the cGAS-STING pathway, is observed in aging cells

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Usually, the next step is to use mass spectrometry to identify those interacting proteins (Kassa et al, 2023)

Glyteine supplementation may also extend to situations where glutathione has been acutely lowered below optimum such as following strenuous exercise and during trauma or poisoning episodes